LZTFL1 anticorps (AA 150-200)
Aperçu rapide pour LZTFL1 anticorps (AA 150-200) (ABIN7449196)
Antigène
Voir toutes LZTFL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 150-200
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Fonction
- Rabbit anti-LZTFL1 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- between AA 150 and 200
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Isotype
- IgG
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Indications d'application
- 1:10,000 - 1:25,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- LZTFL1 (Leucine Zipper Transcription Factor-Like 1 (LZTFL1))
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Autre désignation
- LZTFL1
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Sujet
- Background: LZTFL1 is a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in its gene cause a form of Bardet-Biedl Syndrome, a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This protein may also function as a tumor suppressor, possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. [provided by RefSeq, Feb 2013] [taken from NCBI Entrez Gene (Gene ID: 54585)].
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ID gène
- 54585
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UniProt
- Q9NQ48
Antigène
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